ImmPRESS™ Polymer Detection Empowers High-Performance Immunodetection Results
Vector’s ImmPRESS Polymer Detection Reagents provide researchers with robust, sensitive, and streamlined solutions for high-performance immunohistochemistry (IHC) applications.
The ImmPRESS technology leverages novel conjugation chemistries to create highly sensitive, enzyme-polymer antibody reagents. Our unique micro-polymers of highly active horseradish peroxidase (HRP) or alkaline phosphatase (AP) are combined with affinity-purified and pre-adsorbed secondary antibodies to deliver crisp, sensitive staining of target antibodies with minimal non-specific binding.
Why Choose Our ImmPRESS Polymer Detection System?
Advanced Polymer Detection
Micro-polymer conjugates deliver crisp, high-intensity staining of primary antibody targets, even for membrane, nuclear, and low-abundance antigens.
Simplified IHC Workflow
Ready-to-use, optimized reagents simplify protocols, saving time without compromising sensitivity.
Flexible Enzyme Choices
Two formulation options cover the majority of primary antibody retrieval requirements.
Broad Compatibility
Designed to work with commonly used primary antibody species for seamless integration into existing workflows.
Reliable Performance in Animal Models
Pre-adsorbed formulations reduce cross-reactivity, making them ideal for research on diverse animal and veterinary specimens.
Streamlined Multiplex Staining
Dual enzyme options support multi-target detection while maintaining specificity and signal separation.
Compatible with Manual & Automated Platforms
Designed for flexibility, ImmPRESS reagents perform reliably in both manual staining and automated IHC platforms.
ImmPRESS Reagents to Meet Workflow Requirements
Which kit is right for you?
ImmPRESS kits are built to maximize detection of low or unknown abundance antigens for all circumstances. Whether you are looking for the convenience of a single-step protocol, a streamlined double labeling process, increased sensitivity, or efficient mouse-on-mouse staining with minimal background noise, there is an ImmPRESS kit for every application.
One-Step Detection Kits
- ImmPRESS Polymer Antibody Reagent in the species of your choice, conjugated with peroxidase
- 2.5% Normal Horse Serum for blocking (ready-to-use)
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Two-Step Amplified Detection Kits
- BLOXALL® Endogenous HRP/AP Blocking Solution
- 2.5% Normal serum for blocking non-specific binding
- Amplifier Antibody (either goat anti-mouse IgG or goat anti-rabbit IgG)
- ImmPRESS Excel Amplified HRP Polymer Reagent (anti-goat IgG)
- ImmPACT® DAB EqV Substrate
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Double Staining Kits
- BLOXALL® Blocking Solution
- 2.5% Normal Serum
- ImmPRESS Duet Duet HRP/AP Polymer Reagent
- ImmPRESS HRP Anti-Mouse IgG and ImmPRESS AP Anti-Rabbit IgG
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- ImmPRESS HRP Anti-Mouse IgG and ImmPRESS AP Anti-Rabbit IgG
- ImmPACT® DAB EqV Substrate (HRP, brown)
- ImmPACT® Vector® Red Substrate (AP, magenta)
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ImmPRESS Mouse-on-Mouse Detection
The Mouse-on-Mouse (M.O.M.) ImmPRESS HRP (Peroxidase) Polymer Kit is designed for species-on-species detection by using a proprietary Mouse Ig Blocking Reagent and an HRP polymer reagent to minimize endogenous mouse Ig staining, providing clear and specific antigen detection in mouse tissues, all with a simple, pre-optimized protocol. Use these kits to select for:
- Transgene and knock-out mice models
- Genetically modified mice
- Mouse xenograft tissue
- Normal mouse tissue
ImmPRESS Kit Selection Guide
Choose the optimal ImmPRESS Kit for your application by comparing the type of kit with the target species. For the best results, select the kit with the same species of antibody as the tissue in which it will be used.
Target Species | ImmPRESS HRP | ImmPRESS AP | ImmPRESS HRP Veterinary Reagent | ImmPRESS Excel Amplified Detection | ImmPRESS HRP PLUS Kits | |
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Rabbit | made in horse | |||||
made in goat |
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Mouse | made in horse | |||||
made in goat |
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Mouse (rat adsorbed) | made in horse |
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Mouse & Rabbit | made in horse |
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Rat | made in goat |
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Rat (mouse adsorbed) | made in goat |
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Goat | made in horse |
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Polymer Secondary Antibody and Reagent Technical and Educational Resources
For more information on ImmPRESS polymer technology in immunohistochemistry applications, including automated IHC protocols, explore the following resources.
ImmPRESS Polymer Detection Brochure
Learn more about how ImmPRESS system streamlines workflows while providing sensitivity and excellent signal strength.
Automated IHC Protocols using ImmPRESS Polymer Reagents
Review methodology for implementing ImmPRESS polymer reagents in a variety of automated staining platforms.
Automated Staining Protocol with VectaPlex
Learn how VectaPlex and ImmPRESS enable multiplex staining on the Leica BOND automated stainer.
